Gymnema is known to help reduce diabetes in a number of ways: it blocks sweetness and helps regulate blood sugar by blocking the absorption of sugar in the intestines and stimulating the release of insulin from the pancreas. Gymnema sylvestre contains gymnemic acid, which has been shown to play a role in slowing down the transport of glucose from the digestive system (intestine) to the blood vessels. This helps lower blood sugar levels and hemoglobin A1c levels. Research also proves that Gymnema sylvestre leaves can help in the process of repairing and regenerating pancreatic cells. This process can help the body to produce insulin which is effective for people with type 1 and 2 diabetes.

Stimulates insulin production from beta cells in the pancreas. In addition, this traditional medicine can also increase the absorption of sugar by the muscles and increase insulin sensitivity and inhibition of the α-glucosidase enzyme. So that blood sugar levels can be returned within normal limits

The main component of the bioactive compounds contained in Sambiloto extract is andrographolide. Andrographolide has a wide range of pharmacological aspects including anti-inflammatory, anti-cancer and anti-diabetic properties.